22 cases of primary gastrointestinal lymphoma were reviewed, which were confirmed by operation at the Department of Surgery, City Hospital, East Area of Seoul and Chonnam University Hospital during past 5 years from Mat 1988 to April 1993.
1) The primary sites of lymphoma were stomach in 9 cases(40.9%), small intestine in 7 cases(31.8%), and colon in 4 cases(18.2%). The 2 cases developed synchronously at colon & small intestine.
2) The 7th decade was the most prevalent age group(31.8%), and the ratio of to female was 1.8 : 1.
3) The major symptoms & signs were abdominal pain(86.3%), weight loss(59.1%), and palpable abdominal mass(27.3%). Hunger pain was presented in 44.4% of patients with gastric lymphoma.
4) The histologic findings of lymphoma were histiocytic in 17 cases(77.3%), mixed form in 3 cases(13.6%), and undifferenciated in 2 cases(9.1%) according to the Rappaport classification. In classification by Working formulation, there were
intermediate
grade in 19 cases, high grade in 3 cases.
5) The preoperative complication were intestinal obstruction with intussuception in 3 cases, intestinal perforation in 1 case, and ascites in 1 case.
6) The patients were treated by surgery & postoperative adjuvant chemotherapy or radiotherapy. The curative resection was performed in 86.4%. After operation the 15 cases were treated with various combination chemotherapy; MACOP=B in 8 cases,
COP-BLAM
in 4 cases, BACOP in 2 cases, and CHOP in 1 case. Three patients were treated with postoperative rediotherapy.
7) 5 patients with stageⅢor IV bowel lymphoma had died between 1 month & 5 months after operation. The major causes of death were sepsis.
8) One case of gastric pseudolymphoma was revealed multiple lymphomatous polyposis on 4 years & 5 months after operation.
9) The mean survival time were longer in stageⅠ&ⅡthanⅢIV, in male than female, in stomach than bowel.
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